Caskin1 | CASK interacting protein 1

GeneMGI:2442952Synonyms: 3300002N10Rik, C630036E02Rik

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Pigmentation Integument Nervous system Behavior/neurological Mortality/aging Renal/urinary system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:74Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



abnormal coat/hair pigmentation	3 supporting datasets	Caskin1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.97x10^-8
decreased prepulse inhibition	2 supporting datasets	Caskin1^em1(IMPC)Mbp	homozygote	Early adult	7.26x10^-11
decreased locomotor activity	1 supporting dataset	Caskin1^em1(IMPC)Mbp	homozygote	Early adult	7.02x10^-22
preweaning lethality, incomplete penetrance	3 supporting datasets	Caskin1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
cystolithiasis	1 supporting dataset	Caskin1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Caskin1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
abnormal urinary bladder morphology	1 supporting dataset	Caskin1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
increased respiratory quotient	1 supporting dataset	Caskin1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.6x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Caskin1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Caskin1.

IMPC related publications

Loading...

External links

No external links available for Caskin1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Caskin1^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Caskin1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Caskin1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Caskin1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Caskin1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes