Minar2 | membrane integral NOTCH2 associated receptor 2

GeneMGI:2442934Synonyms: A730017C20Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hearing/vestibular/ear Behavior/neurological Skeleton

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal auditory brainstem response	6 supporting datasets	Minar2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.1x10^-12
decreased lean body mass	2 supporting datasets	Minar2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.93x10^-9
absent pinna reflex	1 supporting dataset	Minar2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.99x10^-18
increased total body fat amount	2 supporting datasets	Minar2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.26x10^-9
decreased bone mineral density	1 supporting dataset	Minar2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.89x10^-8
decreased bone mineral content	2 supporting datasets	Minar2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.05x10^-12
decreased circulating glucose level	1 supporting dataset	Minar2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.02x10^-5
abnormal bone structure	1 supporting dataset	Minar2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.98x10^-5
decreased body length	1 supporting dataset	Minar2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.6x10^-6
decreased circulating phosphate level	1 supporting dataset	Minar2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.29x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Minar2.

Associated images

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Histopathology

There is no histopathology data found for Minar2.

IMPC related publications

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External links

No external links available for Minar2.

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*Minar2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Minar2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Minar2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Minar2^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Minar2^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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