Rab11fip4 | RAB11 family interacting protein 4 (class II)

GeneMGI:2442920Synonyms: A730072L08Rik, RAB11-FIP4

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetRab11fip4em1(IMPC)JhomozygoteEarly adult2.79x10-5 
decreased thigmotaxis2 supporting datasetsRab11fip4em1(IMPC)JhomozygoteEarly adult3.82x10-6 
abnormal behavior1 supporting datasetRab11fip4em1(IMPC)JhomozygoteEarly adult3.85x10-6 
increased exploration in new environment1 supporting datasetRab11fip4em1(IMPC)JhomozygoteEarly adult4.79x10-7 
hyperactivity1 supporting datasetRab11fip4em1(IMPC)JhomozygoteEarly adult6.78x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rab11fip4em1(IMPC)JExon Deletionmouse
Rab11fip4tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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