Clptm1l | CLPTM1-like

GeneMGI:2442892Synonyms: C130052I12Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological Skeleton

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased exploration in new environment1 supporting datasetClptm1lem1(IMPC)JhomozygoteEarly adult1.04x10-7 
hyperactivity7 supporting datasetsClptm1lem1(IMPC)JhomozygoteEarly adult2.99x10-10 
increased vertical activity1 supporting datasetClptm1lem1(IMPC)JhomozygoteEarly adult3.89x10-6 
decreased circulating alkaline phosphatase level1 supporting datasetClptm1lem1(IMPC)JhomozygoteEarly adult3.47x10-16 
increased prepulse inhibition1 supporting datasetClptm1lem1(IMPC)JhomozygoteEarly adult6.33x10-5 
decreased grip strength1 supporting datasetClptm1lem1(IMPC)JhomozygoteEarly adult9.51x10-5 
hyperactivity5 supporting datasetsClptm1lem1(IMPC)JhomozygoteLate adult7.32x10-9 
decreased locomotor activity1 supporting datasetClptm1lem1(IMPC)JhomozygoteLate adult2.54x10-5 
cataract1 supporting datasetClptm1lem1(IMPC)JhomozygoteEarly adult3.61x10-5 
decreased bone mineral content1 supporting datasetClptm1lem1(IMPC)JhomozygoteEarly adult3.28x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Clptm1lem1(IMPC)JExon Deletionmouse
Clptm1ltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Clptm1ltm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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