Rigi | RNA sensor RIG-I

GeneMGI:2442858Synonyms: 6430573D20Rik, RIG-I, +2 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument Liver/biliary system Behavior/neurological

15 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

small liver1 supporting datasetRigiem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal coat/hair pigmentation1 supporting datasetRigiem1(IMPC)JhomozygoteEarly adult7.02x10-8 
abnormal liver morphology1 supporting datasetRigiem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vocalization1 supporting datasetRigiem1(IMPC)JhomozygoteEarly adult5.85x10-8 
impaired glucose tolerance1 supporting datasetRigiem1(IMPC)MbphomozygoteEarly adult4.38x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rigiem1(IMPC)JExon Deletionmouse
Rigiem1(IMPC)MbpExon Deletionmouse
Rigitm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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