Paxx | non-homologous end joining factor

GeneMGI:2442831Synonyms: D930050G13Rik, BC029214, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Reproductive system Immune system Behavior/neurological

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased freezing behavior1 supporting datasetPaxxem1(IMPC)MbphomozygoteEarly adult4.21x10-6 
abnormal lymph node morphology1 supporting datasetPaxxem1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetPaxxem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal uterus morphology1 supporting datasetPaxxem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Paxxem1(IMPC)MbpExon Deletionmouse
Paxxtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Paxxtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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