Tbc1d32 | TBC1 domain family, member 32

GeneMGI:2442827Synonyms: D630037F22Rik, C6orf170, +2 more

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Digestive/alimentary Vision/eye Cardiovascular system Mortality/aging Craniofacial

10 No significant impact

5 Not tested

Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetTbc1d32em1(IMPC)JhomozygoteE18.5N/A * 
polydactyly1 supporting datasetTbc1d32em1(IMPC)JhomozygoteE18.5N/A * 
hemorrhage1 supporting datasetTbc1d32em1(IMPC)JhomozygoteE18.5N/A * 
facial cleft1 supporting datasetTbc1d32em1(IMPC)JhomozygoteE18.5N/A * 
anophthalmia1 supporting datasetTbc1d32em1(IMPC)JhomozygoteE18.5N/A * 
abnormal body wall morphology1 supporting datasetTbc1d32em1(IMPC)JhomozygoteE18.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetTbc1d32em1(IMPC)JhomozygoteEarly adultN/A * 
cleft palate1 supporting datasetTbc1d32em1(IMPC)JhomozygoteE18.5N/A * 
edema1 supporting datasetTbc1d32em1(IMPC)JhomozygoteE18.5N/A * 
abnormal facial morphology1 supporting datasetTbc1d32em1(IMPC)JhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tbc1d32em1(IMPC)JExon Deletionmouse

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