Dennd1a | DENN domain containing 1A
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Nervous system Mortality/aging Cardiovascular system
17 No significant impact
2 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal neural tube morphology | 1 supporting dataset | Dennd1aem1(IMPC)Mbp | heterozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Dennd1aem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal embryo turning | 1 supporting dataset | Dennd1aem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal forebrain development | 1 supporting dataset | Dennd1aem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal neural tube closure | 1 supporting dataset | Dennd1aem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal placenta morphology | 1 supporting dataset | Dennd1aem1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| abnormal neural tube closure | 1 supporting dataset | Dennd1aem1(IMPC)Mbp | heterozygote | E9.5 | N/A * | ||
| abnormal hindbrain development | 1 supporting dataset | Dennd1aem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Dennd1aem1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal neural tube morphology | 1 supporting dataset | Dennd1aem1(IMPC)Mbp | homozygote | E9.5 | N/A * |
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External links
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| Dennd1aem1(IMPC)Mbp | Exon Deletion | | mouse |
| Dennd1atm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Dennd1atm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |