Tmem72 | transmembrane protein 72

GeneMGI:2442707Synonyms: C230095G01Rik

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal coat/hair pigmentation	2 supporting datasets	Tmem72^{tm1b(KOMP)Wtsi}	homozygote	Late adult	1.19x10^-7
increased lean body mass	1 supporting dataset	Tmem72^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.06x10^-9
increased erythrocyte cell number	1 supporting dataset	Tmem72^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.66x10^-6
increased hemoglobin content	1 supporting dataset	Tmem72^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.69x10^-5
increased startle reflex	1 supporting dataset	Tmem72^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.55x10^-6
increased grip strength	2 supporting datasets	Tmem72^{tm1b(KOMP)Wtsi}	homozygote	Late adult	2.33x10^-5
increased grip strength	2 supporting datasets	Tmem72^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.55x10^-7
decreased total body fat amount	1 supporting dataset	Tmem72^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.15x10^-11
decreased blood urea nitrogen level	1 supporting dataset	Tmem72^{tm1b(KOMP)Wtsi}	homozygote	Late adult	3.44x10^-5
increased hematocrit	1 supporting dataset	Tmem72^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.73x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem72.

Associated images

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Histopathology

There is no histopathology data found for Tmem72.

IMPC related publications

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External links

No external links available for Tmem72.

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*Tmem72^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tmem72^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tmem72^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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