Frrs1l | ferric-chelate reductase 1 like

GeneMGI:2442704Synonyms: 6430704M03Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Integument Nervous system Behavior/neurological Mortality/aging

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

3Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal gait	1 supporting dataset	Frrs1l^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.89x10^-16
abnormal locomotor behavior	1 supporting dataset	Frrs1l^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.6x10^-11
decreased grip strength	2 supporting datasets	Frrs1l^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.52x10^-5
hyperactivity	8 supporting datasets	Frrs1l^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	0
absent vibrissae	1 supporting dataset	Frrs1l^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.92x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Frrs1l^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
limb grasping	1 supporting dataset	Frrs1l^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.02x10^-14
decreased prepulse inhibition	1 supporting dataset	Frrs1l^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.13x10^-5
trunk curl	1 supporting dataset	Frrs1l^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.49x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Frrs1l.

Associated images

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Histopathology

There is no histopathology data found for Frrs1l.

IMPC related publications

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External links

No external links available for Frrs1l.

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*Frrs1l^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Frrs1l^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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