Frrs1l | ferric-chelate reductase 1 like
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Integument Nervous system Behavior/neurological Mortality/aging
13 No significant impact
7 Not tested
Gene metrics:9Significant phenotypes
3Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
abnormal gait | 1 supporting dataset | Frrs1ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 6.89x10-16 | ||
abnormal locomotor behavior | 1 supporting dataset | Frrs1ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.6x10-11 | ||
decreased grip strength | 2 supporting datasets | Frrs1ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.52x10-5 | ||
hyperactivity | 8 supporting datasets | Frrs1ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 0 | ||
absent vibrissae | 1 supporting dataset | Frrs1ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 7.92x10-5 | ||
preweaning lethality, incomplete penetrance | 1 supporting dataset | Frrs1ltm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
limb grasping | 1 supporting dataset | Frrs1ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.02x10-14 | ||
decreased prepulse inhibition | 1 supporting dataset | Frrs1ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.13x10-5 | ||
trunk curl | 1 supporting dataset | Frrs1ltm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.49x10-6 |
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External links
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Frrs1ltm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Frrs1ltm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |