Creb3l2 | cAMP responsive element binding protein 3-like 2

GeneMGI:2442695Synonyms: C530025K05Rik, BBF2H7

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology2 supporting datasetsCreb3l2em1(IMPC)CcpczheterozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetCreb3l2em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal spleen morphology2 supporting datasetsCreb3l2em1(IMPC)CcpczheterozygoteEarly adultN/A * 
cataract1 supporting datasetCreb3l2em1(IMPC)CcpczheterozygoteEarly adult8.04x10-5 
increased freezing behavior1 supporting datasetCreb3l2em1(IMPC)CcpczheterozygoteEarly adult1.92x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Creb3l2em1(IMPC)CcpczExon Deletionmouse
Creb3l2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Creb3l2tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Creb3l2tm41898(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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