Lrrc49 | leucine rich repeat containing 49

GeneMGI:2442689Synonyms: D430025H09Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

15 No significant impact

7 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

decreased vertical activity1 supporting datasetLrrc49tm1b(EUCOMM)WtsiheterozygoteEarly adult3.91x10-6 
preweaning lethality, incomplete penetrance1 supporting datasetLrrc49tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal sleep behavior1 supporting datasetLrrc49tm1b(EUCOMM)WtsiheterozygoteEarly adult5.28x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lrrc49tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Lrrc49tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lrrc49tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Lrrc49tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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