Slc30a8 | solute carrier family 30 (zinc transporter), member 8

GeneMGI:2442682Synonyms: ZnT-8, ZnT8, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Vision/eye

16 No significant impact

5 Not tested

Gene metrics:10Significant phenotypes
1Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetSlc30a8tm1a(KOMP)WtsihomozygoteEarly adult6.21x10-5 
increased circulating alanine transaminase level1 supporting datasetSlc30a8tm1a(KOMP)WtsihomozygoteEarly adult9.15x10-6 
increased circulating aspartate transaminase level1 supporting datasetSlc30a8tm1a(KOMP)WtsihomozygoteEarly adult1.92x10-8 
abnormal retina pigmentation1 supporting datasetSlc30a8tm1a(KOMP)WtsihomozygoteEarly adult5.96x10-5 
increased circulating alkaline phosphatase level1 supporting datasetSlc30a8tm1a(KOMP)WtsihomozygoteEarly adult1.08x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Slc30a8tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Slc30a8tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Slc30a8tm42535(L1L2_Pgk_PM)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter