Hectd2 | HECT domain E3 ubiquitin protein ligase 2

GeneMGI:2442663Synonyms: A630025O09Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Behavior/neurological Skeleton

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



abnormal epididymis morphology	1 supporting dataset	Hectd2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased grip strength	1 supporting dataset	Hectd2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.29x10^-5
abnormal scapula morphology	1 supporting dataset	Hectd2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.93x10^-7
decreased bone mineral content	2 supporting datasets	Hectd2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.07x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hectd2.

Associated images

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Histopathology

There is no histopathology data found for Hectd2.

IMPC related publications

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External links

No external links available for Hectd2.

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*Hectd2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Hectd2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hectd2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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