Frmd5 | FERM domain containing 5

GeneMGI:2442557Synonyms: 1500032A09Rik, A930004K21Rik

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Pigmentation Adipose tissue Growth/size/body region Nervous system Vision/eye Behavior/neurological Mortality/aging

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



hyperactivity	1 supporting dataset	Frmd5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.47x10^-5
decreased grip strength	2 supporting datasets	Frmd5^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.05x10^-5
decreased prepulse inhibition	5 supporting datasets	Frmd5^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.53x10^-8
abnormal eye morphology	1 supporting dataset	Frmd5^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.11x10^-5
abnormal lens morphology	1 supporting dataset	Frmd5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.58x10^-6
increased total body fat amount	1 supporting dataset	Frmd5^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.08x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Frmd5^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased lean body mass	1 supporting dataset	Frmd5^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.61x10^-5
female infertility	1 supporting dataset	Frmd5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal retina pigmentation	2 supporting datasets	Frmd5^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Frmd5.

Associated images

Loading...

Histopathology

There is no histopathology data found for Frmd5.

IMPC related publications

Loading...

External links

No external links available for Frmd5.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Frmd5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Frmd5^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Frmd5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes