Dis3l2 | DIS3 like 3'-5' exoribonuclease 2
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Limbs/digits/tail Cardiovascular system Mortality/aging
13 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal embryo size | 1 supporting dataset | Dis3l2em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| hemorrhage | 1 supporting dataset | Dis3l2em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Dis3l2em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal tail morphology | 1 supporting dataset | Dis3l2em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| increased body length | 1 supporting dataset | Dis3l2em1(IMPC)Bay | heterozygote | Early adult | 3.54x10-6 |
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External links
No external links available for Dis3l2.
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| Dis3l2em1(IMPC)Bay | Exon Deletion | | mouse |
| Dis3l2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Dis3l2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |