Dgkb | diacylglycerol kinase, beta

GeneMGI:2442474Synonyms: DGK-beta, C630029D13Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Cardiovascular system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength2 supporting datasetsDgkbem1(IMPC)JhomozygoteEarly adult3x10-5 
prolonged RR interval1 supporting datasetDgkbem1(IMPC)JhomozygoteEarly adult8.77x10-6 
hyperactivity2 supporting datasetsDgkbem1(IMPC)JhomozygoteEarly adult8.8x10-5 
decreased heart rate1 supporting datasetDgkbem1(IMPC)JhomozygoteEarly adult5.76x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dgkbem1(IMPC)JExon Deletionmouse
Dgkbtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dgkbtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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