Irf2bpl | interferon regulatory factor 2 binding protein-like

GeneMGI:2442463Synonyms: 6430527G18Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetIrf2bplem2(IMPC)BayheterozygoteEarly adult4.82x10-6 
preweaning lethality, incomplete penetrance2 supporting datasetsIrf2bplem2(IMPC)BayhomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsIrf2bplem1(IMPC)BayhomozygoteEarly adultN/A * 
decreased locomotor activity2 supporting datasetsIrf2bplem2(IMPC)BayheterozygoteEarly adult8.74x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Irf2bplem1(IMPC)BayWhole-gene deletionmouse
Irf2bplem2(IMPC)BayPoint Mutationmouse
Irf2bpltm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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