Syne3 | spectrin repeat containing, nuclear envelope family member 3

GeneMGI:2442408Synonyms: nesprin-3alpha, nesprin-3beta, +2 more

Physiological systems

21 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

20 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes



increased circulating triglyceride level	1 supporting dataset	Syne3^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.64x10^-5
decreased circulating glucose level	1 supporting dataset	Syne3^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.63x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Syne3.

Associated images

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Histopathology

There is no histopathology data found for Syne3.

IMPC related publications

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External links

No external links available for Syne3.

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*Syne3^{tm113163(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Syne3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Syne3^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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