Efcab14 | EF-hand calcium binding domain 14

GeneMGI:2442397Synonyms: 4732418C07Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Skeleton Cardiovascular system

15 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

increased bone mineral content2 supporting datasetsEfcab14tm1b(KOMP)WtsihomozygoteEarly adult1.11x10-5 
decreased total retina thickness2 supporting datasetsEfcab14tm1b(KOMP)WtsihomozygoteEarly adult1.5x10-15 
dilated heart left ventricle1 supporting datasetEfcab14tm1b(KOMP)WtsihomozygoteEarly adult9.19x10-5 
abnormal retina inner nuclear layer morphology2 supporting datasetsEfcab14tm1b(KOMP)WtsihomozygoteEarly adult3.31x10-7 
abnormal retina outer nuclear layer morphology1 supporting datasetEfcab14tm1b(KOMP)WtsihomozygoteEarly adult5.07x10-6 
decreased heart rate1 supporting datasetEfcab14tm1b(KOMP)WtsihomozygoteEarly adult1.71x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Efcab14tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Efcab14tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Efcab14tm36624(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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