Ipo11 | importin 11

GeneMGI:2442377Synonyms: 1700081H05Rik, Ranbp11, +2 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Mortality/aging

17 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetIpo11tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal lens morphology1 supporting datasetIpo11tm1.1(KOMP)VlcgheterozygoteEarly adult1.21x10-5 
increased fasting circulating glucose level1 supporting datasetIpo11tm1.1(KOMP)VlcgheterozygoteEarly adult1.87x10-6 
decreased circulating glucose level1 supporting datasetIpo11tm1.1(KOMP)VlcgheterozygoteEarly adult1.41x10-5 
decreased circulating iron level1 supporting datasetIpo11tm1.1(KOMP)VlcgheterozygoteEarly adult9.66x10-5 
embryonic lethality prior to tooth bud stage1 supporting datasetIpo11tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ipo11tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Ipo11tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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