Kdm4b | lysine (K)-specific demethylase 4B
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Mortality/aging Cardiovascular system
16 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Kdm4btm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased heart weight | 1 supporting dataset | Kdm4btm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.12x10-8 | ||
| increased circulating creatinine level | 1 supporting dataset | Kdm4btm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.09x10-7 | ||
| decreased circulating serum albumin level | 1 supporting dataset | Kdm4btm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.35x10-5 | ||
| decreased circulating total protein level | 1 supporting dataset | Kdm4btm1a(EUCOMM)Wtsi | heterozygote | Early adult | 7.84x10-5 | ||
| increased circulating magnesium level | 1 supporting dataset | Kdm4btm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.2x10-5 |
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External links
No external links available for Kdm4b.
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| Kdm4btm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Kdm4btm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |