Lingo2 | leucine rich repeat and Ig domain containing 2

GeneMGI:2442298Synonyms: LERN3, Lrrn6c, +1 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Adipose tissue Growth/size/body region Limbs/digits/tail Liver/biliary system Skeleton

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased lean body mass	1 supporting dataset	Lingo2^{em1(IMPC)Kmpc}	homozygote	Late adult	1.02x10^-7
decreased total body fat amount	1 supporting dataset	Lingo2^{em1(IMPC)Kmpc}	homozygote	Early adult	1.14x10^-5
increased lean body mass	1 supporting dataset	Lingo2^{em1(IMPC)Kmpc}	homozygote	Early adult	2.99x10^-6
hydrometra	1 supporting dataset	Lingo2^{em1(IMPC)Kmpc}	homozygote	Late adult	N/A ^*
long tibia	1 supporting dataset	Lingo2^{em1(IMPC)Kmpc}	homozygote	Early adult	1.26x10^-5
increased bone mineral content	1 supporting dataset	Lingo2^{em1(IMPC)Kmpc}	homozygote	Early adult	6.73x10^-5
increased body length	1 supporting dataset	Lingo2^{em1(IMPC)Kmpc}	homozygote	Early adult	2.44x10^-8
abnormal liver morphology	1 supporting dataset	Lingo2^{em1(IMPC)Kmpc}	homozygote	Late adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Lingo2^{em1(IMPC)Kmpc}	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Lingo2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Lingo2.

IMPC related publications

Loading...

External links

No external links available for Lingo2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Lingo2^{em1(IMPC)Kmpc}*	Deletion	‌	mouse
*Lingo2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Lingo2^{tm47327(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes