Proser2 | proline and serine rich 2

GeneMGI:2442238Synonyms: 5430407P10Rik

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged thymus	1 supporting dataset	Proser2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
thin ventricular wall	1 supporting dataset	Proser2^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.26x10^-6
abnormal thymus morphology	1 supporting dataset	Proser2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal urinary bladder morphology	1 supporting dataset	Proser2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Proser2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased circulating chloride level	1 supporting dataset	Proser2^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.44x10^-6
enlarged spleen	1 supporting dataset	Proser2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased startle reflex	1 supporting dataset	Proser2^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.74x10^-6
enlarged lymph nodes	1 supporting dataset	Proser2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Proser2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Proser2.

Associated images

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Histopathology

There is no histopathology data found for Proser2.

IMPC related publications

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External links

No external links available for Proser2.

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*Proser2^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Proser2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Proser2^{tm39280(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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