Mfn2 | mitofusin 2

GeneMGI:2442230Synonyms: Fzo, hypertension related protein 1, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Behavior/neurological Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

9Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal gait	1 supporting dataset	Mfn2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.96x10^-5
decreased lean body mass	1 supporting dataset	Mfn2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	7.17x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Mfn2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Mfn2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Mfn2.

IMPC related publications

Loading...

External links

No external links available for Mfn2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Mfn2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Mfn2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes