Pdpr | pyruvate dehydrogenase phosphatase regulatory subunit
Physiological systems
16 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological
12 No significant impact
8 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased large unstained cell number | 2 supporting datasets | Pdprtm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.69x10-7 | ||
| improved glucose tolerance | 2 supporting datasets | Pdprtm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.73x10-10 | ||
| abnormal cholesterol homeostasis | 1 supporting dataset | Pdprtm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.59x10-5 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Pdprtm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.85x10-14 | ||
| increased hematocrit | 1 supporting dataset | Pdprtm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.3x10-5 | ||
| decreased locomotor activity | 2 supporting datasets | Pdprtm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.68x10-5 | ||
| decreased circulating creatinine level | 1 supporting dataset | Pdprtm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.26x10-5 |
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External links
No external links available for Pdpr.
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| Pdprtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Pdprtm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Pdprtm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |