Trub2 | TruB pseudouridine (psi) synthase family member 2

GeneMGI:2442186Synonyms: G430055L02Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Trub2^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating cholesterol level	1 supporting dataset	Trub2^{tm2a(EUCOMM)Wtsi}	heterozygote	Early adult	3.56x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Trub2.

Associated images

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Histopathology

There is no histopathology data found for Trub2.

IMPC related publications

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External links

No external links available for Trub2.

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*Trub2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Trub2^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Trub2^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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