Dnajc16 | DnaJ heat shock protein family (Hsp40) member C16

GeneMGI:2442146Synonyms: 4732437J24Rik, 2900037O03Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Embryo Limbs/digits/tail Hearing/vestibular/ear Mortality/aging

15 No significant impact

5 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
44Embryo tissues

Phenotypes

abnormal limb bud morphology1 supporting datasetDnajc16tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
abnormal auditory brainstem response1 supporting datasetDnajc16tm1.1(KOMP)VlcgheterozygoteEarly adult6.82x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetDnajc16tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dnajc16tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Dnajc16tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Dnajc16tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dnajc16tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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