Wdr59 | WD repeat domain 59
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Hematopoietic system Mortality/aging
16 No significant impact
3 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Wdr59tm1b(EUCOMM)Wtsi | homozygote | E15.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Wdr59tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| decreased hematocrit | 1 supporting dataset | Wdr59tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 4.74x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Wdr59tm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| decreased leukocyte cell number | 1 supporting dataset | Wdr59tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3x10-5 | ||
| prenatal lethality | 1 supporting dataset | Wdr59tm1b(EUCOMM)Wtsi | homozygote | E18.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Wdr59tm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| decreased erythrocyte cell number | 1 supporting dataset | Wdr59tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 6.92x10-5 | ||
| decreased hemoglobin content | 1 supporting dataset | Wdr59tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2.73x10-7 |
| | | | | | | | | | |
External links
No external links available for Wdr59.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Wdr59tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Wdr59tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Wdr59tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |