Arhgef11 | Rho guanine nucleotide exchange factor 11

GeneMGI:2441869Synonyms: Prg, PDZ-RhoGEF

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	1 supporting dataset	Arhgef11^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.47x10^-11
increased aggression	1 supporting dataset	Arhgef11^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.82x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arhgef11.

Associated images

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Histopathology

There is no histopathology data found for Arhgef11.

IMPC related publications

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External links

No external links available for Arhgef11.

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*Arhgef11^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Arhgef11^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes