Arhgef11 | Rho guanine nucleotide exchange factor 11

GeneMGI:2441869Synonyms: Prg, PDZ-RhoGEF

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	1 supporting dataset	Arhgef11^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.47x10^-11
increased aggression	1 supporting dataset	Arhgef11^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.82x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Arhgef11.

Associated images

Loading...

Histopathology

There is no histopathology data found for Arhgef11.

IMPC related publications

Loading...

External links

No external links available for Arhgef11.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Arhgef11^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Arhgef11^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes