Lpp | LIM domain containing preferred translocation partner in lipoma

GeneMGI:2441849Synonyms: B130055L10Rik, 9430020K16Rik

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Nervous system Vision/eye Liver/biliary system Cardiovascular system Mortality/aging

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

1Associated diseases

Expression examined in:78Adult tissues

35Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal liver morphology	2 supporting datasets	Lpp^{tm1b(KOMP)Wtsi}	homozygote	Late adult	N/A ^*
abnormal retina blood vessel morphology	1 supporting dataset	Lpp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.76x10^-8
persistence of hyaloid vascular system	1 supporting dataset	Lpp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.45x10^-6
abnormal retina vasculature morphology	1 supporting dataset	Lpp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.91x10^-7
abnormal body fat mass	1 supporting dataset	Lpp^{tm1b(KOMP)Wtsi}	homozygote	Late adult	1.11x10^-7
abnormal retina morphology	1 supporting dataset	Lpp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.23x10^-6
increased circulating phosphate level	1 supporting dataset	Lpp^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.01x10^-7
preweaning lethality, incomplete penetrance	1 supporting dataset	Lpp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal optic disk morphology	1 supporting dataset	Lpp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.09x10^-7
abnormal lean body mass	1 supporting dataset	Lpp^{tm1b(KOMP)Wtsi}	homozygote	Late adult	7.16x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Lpp.

Associated images

Loading...

Histopathology

There is no histopathology data found for Lpp.

IMPC related publications

Loading...

External links

No external links available for Lpp.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Lpp^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Lpp^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes