Lgr6 | leucine-rich repeat-containing G protein-coupled receptor 6

GeneMGI:2441805Synonyms: A530037C04Rik

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Integument Growth/size/body region Vision/eye Hematopoietic system Skeleton Cardiovascular system Craniofacial

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal heart morphology1 supporting datasetLgr6em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetLgr6em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal tooth morphology1 supporting datasetLgr6em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetLgr6em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal skin morphology2 supporting datasetsLgr6em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology2 supporting datasetsLgr6em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetLgr6em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetLgr6em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lgr6em1(IMPC)CcpczInter-exon deletionmouse
Lgr6tm102274(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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