Pgbd5 | piggyBac transposable element derived 5

GeneMGI:2429955Synonyms: 2900019M05Rik

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Endocrine/exocrine gland Adipose tissue Growth/size/body region Digestive/alimentary Vision/eye Behavior/neurological Skeleton Renal/urinary system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal sternum morphology	2 supporting datasets	Pgbd5^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Pgbd5^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
impaired contextual conditioning behavior	1 supporting dataset	Pgbd5^em1(IMPC)Tcp	homozygote	Early adult	2.87x10^-5
increased total body fat amount	1 supporting dataset	Pgbd5^em1(IMPC)Tcp	homozygote	Early adult	6.25x10^-5
hyperactivity	2 supporting datasets	Pgbd5^em1(IMPC)Tcp	homozygote	Early adult	2.4x10^-9
increased grip strength	1 supporting dataset	Pgbd5^em1(IMPC)Tcp	homozygote	Early adult	1.57x10^-5
impaired glucose tolerance	1 supporting dataset	Pgbd5^em1(IMPC)Tcp	homozygote	Early adult	9.54x10^-5
enlarged salivary gland	1 supporting dataset	Pgbd5^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased circulating alanine transaminase level	1 supporting dataset	Pgbd5^em1(IMPC)Tcp	homozygote	Early adult	5.64x10^-6
anophthalmia	1 supporting dataset	Pgbd5^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pgbd5.

Associated images

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Histopathology

There is no histopathology data found for Pgbd5.

IMPC related publications

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External links

No external links available for Pgbd5.

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*Pgbd5^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Pgbd5^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pgbd5^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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