Tbc1d4 | TBC1 domain family, member 4
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system
15 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues
| decreased leukocyte cell number | 1 supporting dataset | Tbc1d4tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.99x10-5 | ||
| decreased circulating chloride level | 1 supporting dataset | Tbc1d4tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.78x10-6 | ||
| increased hematocrit | 1 supporting dataset | Tbc1d4tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.86x10-5 | ||
| increased mean corpuscular volume | 1 supporting dataset | Tbc1d4tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.69x10-5 | ||
| increased circulating sodium level | 1 supporting dataset | Tbc1d4tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.11x10-6 |
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External links
No external links available for Tbc1d4.
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| Tbc1d4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Tbc1d4tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Tbc1d4tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |