Adamts16 | ADAM metallopeptidase with thrombospondin type 1 motif 16

GeneMGI:2429637

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Hematopoietic system Behavior/neurological Skeleton

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased bone mineral content	2 supporting datasets	Adamts16^em1(IMPC)H	homozygote	Early adult	8.28x10^-8
decreased circulating potassium level	1 supporting dataset	Adamts16^em1(IMPC)H	homozygote	Early adult	2.64x10^-5
increased circulating HDL cholesterol level	1 supporting dataset	Adamts16^em1(IMPC)H	homozygote	Early adult	3.36x10^-5
increased total body fat amount	1 supporting dataset	Adamts16^em1(IMPC)H	homozygote	Early adult	2.29x10^-5
decreased eosinophil cell number	2 supporting datasets	Adamts16^em1(IMPC)H	homozygote	Early adult	5.12x10^-5
decreased neutrophil cell number	1 supporting dataset	Adamts16^em1(IMPC)H	homozygote	Early adult	2.85x10^-5
tremors	1 supporting dataset	Adamts16^em1(IMPC)H	homozygote	Early adult	4.81x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adamts16.

Associated images

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Histopathology

There is no histopathology data found for Adamts16.

IMPC related publications

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External links

No external links available for Adamts16.

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*Adamts16^em1(IMPC)H*	Exon Deletion	‌	mouse
*Adamts16^em1(IMPC)J*	Exon Deletion	‌	mouse
*Adamts16^em2(IMPC)H*	Exon Deletion	‌	mouse
*Adamts16^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Adamts16^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Adamts16^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Adamts16^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Adamts16^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Adamts16^{tm40100(L1L2_st1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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