Irak2 | interleukin-1 receptor-associated kinase 2

GeneMGI:2429603Synonyms: IRAK-2, 6330415L08Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Limbs/digits/tail Skeleton

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



short tibia	1 supporting dataset	Irak2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.58x10^-6
increased total body fat amount	2 supporting datasets	Irak2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.55x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Irak2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.06x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Irak2.

Associated images

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Histopathology

There is no histopathology data found for Irak2.

IMPC related publications

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External links

No external links available for Irak2.

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*Irak2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Irak2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Irak2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Irak2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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