Maml2 | mastermind like transcriptional coactivator 2

GeneMGI:2389460

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Nervous system Behavior/neurological

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	2 supporting datasets	Maml2^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	1.51x10^-8
decreased thigmotaxis	2 supporting datasets	Maml2^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	1.33x10^-5
decreased exploration in new environment	1 supporting dataset	Maml2^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	1.76x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Maml2.

Associated images

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Histopathology

There is no histopathology data found for Maml2.

IMPC related publications

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External links

No external links available for Maml2.

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*Maml2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Maml2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell mouse
*Maml2^{tm1e.1(EUCOMM)Hmgu}*	Promoter excision from Targeted, non-conditional allele	‌	mouse

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