Emilin3 | elastin microfibril interfacer 3

GeneMGI:2389142Synonyms: 1110013O17Rik, EMILIN-T, +1 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Growth/size/body region Nervous system Vision/eye Behavior/neurological Cardiovascular system

12 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

hyperactivity5 supporting datasetsEmilin3tm1.1(KOMP)VlcghomozygoteEarly adult1.51x10-9 
persistence of hyaloid vascular system1 supporting datasetEmilin3tm1.1(KOMP)VlcghomozygoteEarly adult1.33x10-5 
increased heart weight1 supporting datasetEmilin3tm1.1(KOMP)VlcghomozygoteEarly adult6.2x10-5 
decreased prepulse inhibition1 supporting datasetEmilin3tm1.1(KOMP)VlcghomozygoteEarly adult5.5x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Emilin3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Emilin3tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Emilin3tm351732(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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