Adamtsl4 | ADAMTS-like 4

GeneMGI:2389008Synonyms: Tsrc1

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Integument Vision/eye Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased grip strength	4 supporting datasets	Adamtsl4^em1(IMPC)J	homozygote	Early adult	3.5x10^-7
persistence of hyaloid vascular system	1 supporting dataset	Adamtsl4^em1(IMPC)J	homozygote	Early adult	9.98x10^-6
abnormal placement of pupils	1 supporting dataset	Adamtsl4^em1(IMPC)J	homozygote	Late adult	2.01x10^-8
cataract	1 supporting dataset	Adamtsl4^em1(IMPC)J	homozygote	Late adult	2.79x10^-9
irregularly shaped pupil	1 supporting dataset	Adamtsl4^em1(IMPC)J	homozygote	Late adult	1.06x10^-8
abnormal retina morphology	1 supporting dataset	Adamtsl4^em1(IMPC)J	homozygote	Early adult	4.28x10^-6
increased grip strength	1 supporting dataset	Adamtsl4^em1(IMPC)J	homozygote	Late adult	1.17x10^-5
abnormal coat/ hair morphology	1 supporting dataset	Adamtsl4^em1(IMPC)J	homozygote	Early adult	4.97x10^-8
abnormal startle reflex	1 supporting dataset	Adamtsl4^em1(IMPC)J	homozygote	Late adult	7.66x10^-6
abnormal vibrissa morphology	1 supporting dataset	Adamtsl4^em1(IMPC)J	homozygote	Late adult	2.1x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adamtsl4.

Associated images

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Histopathology

There is no histopathology data found for Adamtsl4.

IMPC related publications

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External links

No external links available for Adamtsl4.

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*Adamtsl4^em1(IMPC)J*	Exon Deletion	‌	mouse
*Adamtsl4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Adamtsl4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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