Abca16 | ATP-binding cassette, sub-family A member 16

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

limb grasping1 supporting datasetAbca16em1(IMPC)JhomozygoteEarly adult4.04x10-5 
increased grip strength1 supporting datasetAbca16em1(IMPC)JhomozygoteLate adult5.18x10-6 
abnormal lens morphology1 supporting datasetAbca16em1(IMPC)JhomozygoteLate adult9.63x10-5 
abnormal cornea morphology1 supporting datasetAbca16em1(IMPC)JhomozygoteLate adult3.8x10-5 
increased grip strength2 supporting datasetsAbca16em1(IMPC)JhomozygoteEarly adult1.36x10-5 
decreased circulating sodium level1 supporting datasetAbca16em1(IMPC)JhomozygoteEarly adult9.86x10-5 
increased circulating aspartate transaminase level1 supporting datasetAbca16em1(IMPC)JhomozygoteLate adult7.15x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Abca16em1(IMPC)JIntra-exon deletionmouse
Abca16tm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Abca16tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Abca16tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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