Retreg2 | reticulophagy regulator family member 2

GeneMGI:2388278Synonyms: Fam134a, MGC47289

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged spleen1 supporting datasetRetreg2em2(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetRetreg2em2(IMPC)CcpczhomozygoteEarly adult2.51x10-8 
increased freezing behavior1 supporting datasetRetreg2em2(IMPC)CcpczhomozygoteEarly adult1.6x10-10 
abnormal heart morphology1 supporting datasetRetreg2em2(IMPC)CcpczhomozygoteEarly adultN/A * 
increased leukocyte cell number1 supporting datasetRetreg2em2(IMPC)CcpczhomozygoteEarly adult3.11x10-5 
abnormal spleen morphology1 supporting datasetRetreg2em2(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Retreg2em2(IMPC)CcpczDeletionmouse
Retreg2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell

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