Fam20a | FAM20A, golgi associated secretory pathway pseudokinase

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Limbs/digits/tail Vision/eye Skeleton Craniofacial Renal/urinary system

14 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

increased bone mineral content1 supporting datasetFam20atm1b(KOMP)WtsihomozygoteEarly adult3.77x10-7 
short tibia1 supporting datasetFam20atm1b(KOMP)WtsihomozygoteEarly adult1x10-10 
decreased total body fat amount1 supporting datasetFam20atm1b(KOMP)WtsihomozygoteEarly adult7.66x10-5 
abnormal tooth morphology2 supporting datasetsFam20atm1b(KOMP)WtsihomozygoteEarly adult2.3x10-6 
cornea opacity1 supporting datasetFam20atm1b(KOMP)WtsihomozygoteEarly adult2.64x10-11 
abnormal kidney morphology1 supporting datasetFam20atm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fam20atm187834(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Fam20atm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Fam20atm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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