Clrn1 | clarin 1

GeneMGI:2388124Synonyms: clarin-1, USH3, +2 more

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Immune system Integument Hearing/vestibular/ear Liver/biliary system Respiratory system Hematopoietic system Behavior/neurological Renal/urinary system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

4Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal auditory brainstem response	6 supporting datasets	Clrn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.22x10^-6
abnormal spleen morphology	1 supporting dataset	Clrn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Clrn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Clrn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal startle reflex	1 supporting dataset	Clrn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.1x10^-16
abnormal lung morphology	1 supporting dataset	Clrn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Clrn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal vibrissa morphology	1 supporting dataset	Clrn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.91x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Clrn1.

Associated images

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Histopathology

There is no histopathology data found for Clrn1.

IMPC related publications

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External links

No external links available for Clrn1.

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*Clrn1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Clrn1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Clrn1^{tm115517(L1L2_Bact_P)}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector
*Clrn1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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