Fam120c | family with sequence similarity 120, member C

GeneMGI:2387687Synonyms: D930001I21Rik, orf34

Physiological systems

15 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Immune system Integument Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton Cardiovascular system Craniofacial Renal/urinary system

6 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased kidney weight2 supporting datasetsFam120cem1(IMPC)CcpczhemizygoteEarly adult9.9x10-11 
abnormal mammary gland morphology1 supporting datasetFam120cem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetFam120cem1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetFam120cem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetFam120cem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal cranium morphology1 supporting datasetFam120cem1(IMPC)CcpczhemizygoteEarly adult9.09x10-5 
abnormal heart morphology1 supporting datasetFam120cem1(IMPC)CcpczhemizygoteEarly adultN/A * 
enlarged heart1 supporting datasetFam120cem1(IMPC)CcpczhemizygoteEarly adultN/A * 
enlarged spleen1 supporting datasetFam120cem1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fam120cem1(IMPC)CcpczExon Deletionmouse
Fam120ctm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Fam120ctm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Fam120ctm40737(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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