Eml3 | echinoderm microtubule associated protein like 3

GeneMGI:2387612

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Hematopoietic system Skeleton Mortality/aging

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased bone mineral content	2 supporting datasets	Eml3^em1(IMPC)J	heterozygote	Early adult	3.61x10^-6
preweaning lethality, incomplete penetrance	3 supporting datasets	Eml3^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased bone mineral density	1 supporting dataset	Eml3^em1(IMPC)J	heterozygote	Early adult	3.45x10^-8
decreased leukocyte cell number	1 supporting dataset	Eml3^em1(IMPC)J	heterozygote	Early adult	2.51x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Eml3.

Associated images

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Histopathology

There is no histopathology data found for Eml3.

IMPC related publications

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External links

No external links available for Eml3.

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*Eml3^em1(IMPC)J*	Exon Deletion	‌	mouse
*Eml3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Eml3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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