Rbm45 | RNA binding motif protein 45

GeneMGI:2387367Synonyms: Drb1, Drbp1, +1 more

Physiological systems

19 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Embryo Growth/size/body region Limbs/digits/tail Vision/eye Skeleton Craniofacial Cardiovascular system Mortality/aging

9 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased lean body mass	2 supporting datasets	Rbm45^em1(IMPC)J	heterozygote	Early adult	8.78x10^-7
polydactyly	1 supporting dataset	Rbm45^em1(IMPC)J	homozygote	E18.5	N/A ^*
edema	1 supporting dataset	Rbm45^em1(IMPC)J	homozygote	E18.5	N/A ^*
abnormal facial morphology	1 supporting dataset	Rbm45^em1(IMPC)J	homozygote	E18.5	N/A ^*
abnormal tail morphology	1 supporting dataset	Rbm45^em1(IMPC)J	homozygote	E18.5	N/A ^*
hemorrhage	1 supporting dataset	Rbm45^em1(IMPC)J	homozygote	E18.5	N/A ^*
abnormal head shape	1 supporting dataset	Rbm45^em1(IMPC)J	homozygote	E18.5	N/A ^*
abnormal embryo size	1 supporting dataset	Rbm45^em1(IMPC)J	homozygote	E18.5	N/A ^*
increased total body fat amount	2 supporting datasets	Rbm45^em1(IMPC)J	heterozygote	Early adult	1.5x10^-8
anophthalmia	1 supporting dataset	Rbm45^em1(IMPC)J	homozygote	E18.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Rbm45.

Associated images

Loading...

Histopathology

There is no histopathology data found for Rbm45.

IMPC related publications

Loading...

External links

No external links available for Rbm45.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Rbm45^em1(IMPC)J*	Exon Deletion	‌	mouse
*Rbm45^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rbm45^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Rbm45^{tm39338(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes