Ift52 | intraflagellar transport 52
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Nervous system Cardiovascular system Mortality/aging
14 No significant impact
4 Not tested
Data collections
Gene metrics:13Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal midbrain development | 1 supporting dataset | Ift52em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
embryonic growth retardation | 1 supporting dataset | Ift52em1(IMPC)Bay | heterozygote | E9.5 | N/A * | ||
abnormal embryo turning | 1 supporting dataset | Ift52em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
pale yolk sac | 1 supporting dataset | Ift52em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Ift52em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
abnormal heart looping | 1 supporting dataset | Ift52em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Ift52em1(IMPC)Bay | homozygote | E12.5 | N/A * | ||
hemorrhage | 1 supporting dataset | Ift52em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
abnormal visceral yolk sac morphology | 1 supporting dataset | Ift52em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
abnormal forebrain development | 1 supporting dataset | Ift52em1(IMPC)Bay | homozygote | E9.5 | N/A * |
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External links
No external links available for Ift52.
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Ift52em1(IMPC)Bay | Exon Deletion | | mouse |
Ift52tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Ift52tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |