Ift52 | intraflagellar transport 52

GeneMGI:2387217Synonyms: NGD5

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Nervous system Cardiovascular system Mortality/aging

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:13Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal midbrain development1 supporting datasetIft52em1(IMPC)BayhomozygoteE9.5N/A * 
embryonic growth retardation1 supporting datasetIft52em1(IMPC)BayheterozygoteE9.5N/A * 
abnormal embryo turning1 supporting datasetIft52em1(IMPC)BayhomozygoteE9.5N/A * 
pale yolk sac1 supporting datasetIft52em1(IMPC)BayhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsIft52em1(IMPC)BayhomozygoteEarly adultN/A * 
abnormal heart looping1 supporting datasetIft52em1(IMPC)BayhomozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetIft52em1(IMPC)BayhomozygoteE12.5N/A * 
hemorrhage1 supporting datasetIft52em1(IMPC)BayhomozygoteE9.5N/A * 
abnormal visceral yolk sac morphology1 supporting datasetIft52em1(IMPC)BayhomozygoteE9.5N/A * 
abnormal forebrain development1 supporting datasetIft52em1(IMPC)BayhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ift52em1(IMPC)BayExon Deletionmouse
Ift52tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ift52tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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