Lnpep | leucyl/cystinyl aminopeptidase

GeneMGI:2387123Synonyms: IRAP, vp165, +3 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Behavior/neurological

15 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity6 supporting datasetsLnpeptm1b(KOMP)WtsihomozygoteEarly adult5.07x10-7 
increased anxiety-related response1 supporting datasetLnpeptm1b(KOMP)WtsihomozygoteEarly adult6.35x10-5 
decreased exploration in new environment2 supporting datasetsLnpeptm1b(KOMP)WtsihomozygoteEarly adult1.13x10-9 
abnormal seminal vesicle morphology1 supporting datasetLnpeptm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lnpeptm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lnpeptm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Lnpeptm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Lnpeptm211260(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector

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