Rasgrp4 | RAS guanyl releasing protein 4

GeneMGI:2386851

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Hematopoietic system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	1 supporting dataset	Rasgrp4^{tm2a(KOMP)Wtsi}	homozygote	Early adult	7.71x10^-6
increased mean platelet volume	1 supporting dataset	Rasgrp4^{tm2a(KOMP)Wtsi}	homozygote	Early adult	9.35x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rasgrp4.

Associated images

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Histopathology

There is no histopathology data found for Rasgrp4.

IMPC related publications

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External links

No external links available for Rasgrp4.

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*Rasgrp4^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Rasgrp4^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Rasgrp4^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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