Abca5 | ATP-binding cassette, sub-family A member 5

GeneMGI:2386607Synonyms: B930033A02Rik, ABC13

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Cardiovascular system Renal/urinary system

15 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged kidney	1 supporting dataset	Abca5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Abca5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Abca5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Abca5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Abca5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	2 supporting datasets	Abca5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	2 supporting datasets	Abca5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged lymph nodes	2 supporting datasets	Abca5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Abca5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Abca5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Abca5.

Associated images

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Histopathology

There is no histopathology data found for Abca5.

IMPC related publications

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External links

No external links available for Abca5.

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*Abca5^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Abca5^{tm127(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Abca5^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Abca5^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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